MOTS-C

• Product Name: MOTS-c

• Peptide Class: Mitochondrial-Derived Peptide (MDP)

• Peptide Sequence: MRWQEMGYIFYPRKLR

• CAS Number: 1627580-64-6

• Molecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂

• Molecular Weight: 2174.6 g/mol

• Purity: ≥99% (HPLC)

• Available Size: 10 mg

• Appearance: White to off-white lyophilized powder

• Grade: Research Grade

MOTS-c is commonly investigated in laboratory studies involving:

• Mitochondrial biology

• Cellular energy metabolism

• Metabolic regulation

• Insulin signaling pathways

• Glucose metabolism

• AMPK signaling

• Exercise physiology

• Oxidative stress biology

• Cellular aging research

• Mitochondrial–nuclear communication

MOTS-c is one of several peptides encoded by mitochondrial DNA that participate in intracellular communication between mitochondria and the nucleus. In laboratory studies, it has been investigated for its involvement in:

• Mitochondrial signaling pathways

• Cellular adaptation to metabolic stress

• Regulation of energy homeostasis

• AMPK-mediated cellular responses

• Nuclear gene regulation

• Cellular stress response mechanisms

Its unique mitochondrial origin makes MOTS-c an important research peptide for studying mitochondrial function and metabolic physiology.

• Store refrigerated at 2–8°C before reconstitution.

• For long-term storage, keep frozen at −20°C.

• Protect from heat, moisture, and direct light.

• Allow the vial to reach room temperature before opening.

• Reconstitute using sterile bacteriostatic water or another suitable laboratory-grade solvent.

• Gently swirl until completely dissolved.

• Avoid vigorous shaking.

• Minimize repeated freeze–thaw cycles following reconstitution.

Every production batch undergoes comprehensive analytical testing, including:

• HPLC Purity Analysis (≥99%)

• Mass Spectrometry Verification

• Peptide Identity Confirmation

• Appearance Inspection

• Batch Quality Control Testing

MOTS-c has become one of the most actively investigated mitochondrial-derived peptides because of its unique genetic origin and its role in studies of mitochondrial signaling and metabolic regulation. Its involvement in cellular energy pathways, stress-response mechanisms, and mitochondrial–nuclear communication has made it a valuable reagent for research in metabolism, aging biology, and mitochondrial physiology.

For Research Use Only.

This product is intended exclusively for scientific and laboratory research. It is not intended for human consumption, veterinary use, or clinical application and has not been approved for the diagnosis, treatment, cure, or prevention of any disease.